Anti-neoplastic effect of chicken anemia virus VP3 protein (apoptin) in Rous sarcoma virus-induced tumours in chicken
نویسندگان
چکیده
منابع مشابه
Cloning and sequence analysis of VP1, VP2 and VP3 genes of Indian chicken anemia virus
Chicken anemia virus was detected by PCR in tissue samples collected from poultry flocks in Gujarat,India. The VP1, VP2 and VP3 gene sequences of CAV from Anand, Gujarat were obtained after cloning thePCR products in pDrive cloning vector. Nucleotide sequence alignment with other CAV sequencesdemonstrated overall identity of 95-98.8%, 98.8-99.8% and 98.8-100% for VP1, VP2 and VP3 regions,respec...
متن کاملChicken anemia virus.
Chicken anemia virus is commonly found in commercially produced chickens and has a worldwide distribution. It is difficult to inactivate thermally or with common disinfectants, which limits the utility of normal sanitization practices. The virus is important because of the disease it produces following transovarian transmission and because of its potential for inducing immunosuppression alone o...
متن کاملDifferences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus.
We have investigated the intracellular location of pp60src in Rous sarcoma virus-transformed rat cells (RR1022) by indirect immunofluorescence microscopy and cell fractionation. Immunofluorescence data suggest that pp60src is predominantly associated with the nuclear envelope and the juxtanuclear reticular membrane structures. The bulk of pp60src and of the associated phosphotransferase activit...
متن کاملThe induction of the Rous sarcoma in heterologous transplants of virus-infected adult chicken tissue.
The capacity of the Rous chicken tumor to survive heterologous transplantation has been demonstrated in both early and late stages of development.'"' Such investigations were concerned with the transformed cell while the question at issue in the present study involves the cell during the process of transformation. It has been observed that adult rabbit skin infected either in vivo or in vitro w...
متن کاملMolecular properties of Rous chicken sarcoma hyaluronic acid-protein complex.
Hyalu ron ic acid (HA), first isolated by Meyer (1r is a compound of considerable biological interest. This polysacchar ide has been found in m a n y an imal tissues, especially those of mesenchymal origin, and in the capsules of some types of bacter ia . Fur thermore , a mucinous polysacchar ide of the HA type was detected and isolated from fowl sarcoma by K a b a t (10) and by Claude (5). The...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 2006
ISSN: 0022-1317,1465-2099
DOI: 10.1099/vir.0.82085-0